The ESC Congress 2025 took place from Friday, August 29 until September 1, 2025, in Madrid, Spain. As the world’s largest gathering of cardiovascular professionals, the congress brought together clinicians, researchers, and thought leaders from across the globe to discuss the latest developments in cardiovascular care. PROFID, and especially the PROFID EHRA trial, had the great opportunity to be presented within several very important sessions.

A scientific session took place focusing on a key clinical and research question: “The Role of the Primary Prevention Defibrillator After Myocardial Infarction in the Era of Modern Heart Failure Therapy.”

The session addressed how evolving therapeutic strategies are changing the landscape of ICD use in primary prevention. It was exceptionally well attended and provided a platform to share current data and future directions from the PROFID project and beyond.

We thank the outstanding session chairs and speakers for their valuable contributions:

• Annamaria Kosztin (Semmelweis University Heart and Vascular Center – Budapest, Hungary)
• Gerhard Hindricks (Charite University Hospital – Berlin, Germany)
• Milos Taborsky (Masaryk Hospital – Usti Nad Labem, Czechia)
• Valentina Kutyifa (University of Rochester – Rochester, United States of America)
• Nikolaos Dagres (Charité – University Medicine Berlin – Berlin, Germany)

See the full session here: ESC Session Link

PROFID Featured on ESC TV Connect

PROFID was also featured in an ESC TV Connect session titled: “Update on Sudden Cardiac Death”

The discussion included contributions from:

• Gerhard Hindricks (Charité University Hospital – Berlin, Germany)
• Nikolaos Dagres (Heart Center Leipzig – Germany)
• Helmut Pürerfellner (Elisabethinen Hospital – Linz, Austria)

This session explored current trends in SCD prevention and the significance of PROFID’s clinical trials in influencing future clinical practice.
See the full session here: Update on sudden cardiac death: current landscape and challenges in sudden cardiac death prevention

PROFID EHRA Trial Meetings

On August 31, meetings with the Steering Committee, National Coordinators, and the Principal Investigators of the PROFID EHRA trial were successfully held. These meetings provided an excellent opportunity to align on the progress of the trial and reinforce the importance of our collective efforts in enhancing patient enrollment.